- Flying - Immune to ground attacks
- Move 1 - Soul consumption. Debuffs - soul loss. Buffs - Soul link. One enemy.
- Move 2 - Fire from hell. Debuffs - burning, soul fire. Buffs - none. All enemies
- Move 3 - Self redemption. Buff - fired up. Self
- Move 4 - Soul Burner. Debuff - soul fire. Buffs - none. One enemy
Santana has the following team-up bonuses.
Aviary, Highway to Hell, Hot stuff, Red in the ledger, Thunderbolts, and hellions(daimon hellstorm and Satana).