- The Red Skull was first seen in Marvel: Avengers Alliance's trailer video.
- Red Skull has a themed weapon: Tesseract Simulation Device.
- Red Skull is the Group Boss for Spec Ops 10 and the second Group Boss in Marvel: Avengers Alliance
- Red Skull's Cosmic Cube changes color with his class change in Spec Ops 10.
- Even if Red Skull is defeated, the Group Boss battle will not end if there are any enemies summoned by him in battle.
- Red Skull is the father of Sin.
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